Blended gasoline will equal a few miles less per tank.
If I drive highway w/some local driving I can get around 33 mpg.
If I drive to/from work every day w/no highway driving, and this is local w/stops and about 10 miles total, I get less than 20 mpg and it will get worse w/blended gas. This is because the car never really has a chance to warmup to a good operating temperature. In addition, this means that the oil & filter should be changed more often because this is considered to be in the area of severe driving conditions.
If I do mostly local driving, let's say 20-40 miles a day I get about 24 mpg.
Temperature (outside and/or engine thermostat), blended gasoline, frequency of stop/start all affect mpg.
Just wait and see if fuel prices really spike up at least 40-cents a gallon because, supposedly, the blended gas is not only expensive to make, but they're going to use gasahol (corn derivative) as opposed to methanol (MTBE) or ethanol (ETBE); $2.39 for a gallon? Fuel is already $1.89/gal. here.