You mean the Xcalibrator? It all depends on the program you use, but it's certainly possible to have a nitrous program made for your setup.
However, IMO, nitrous is the stock PCM's achilles heel because there's no way for the PCM to "know" when you're spraying. For that reason, I suggest using a J&S Safeguard to 1.) listen for knock and automatically retard the timing and 2.) automatically retard the timing either 2 or 4 degrees when the nitrous is activated.
A multi-program chip is ideal for nitrous, since it allows you to quickly change to your nitrous file. But a flasher will also work - it's just that you'll have to compromise a bit.